Highly regioselective synthesis of 2,4,5-(hetero)aryl substituted oxazoles by intermolecular [3+2]-cycloaddition of unsymmetrical internal alkynes.
نویسندگان
چکیده
A robust N-nucleophilic 1,3-N,O-dipole equivalent reacts with unsymmetrical internal alkynes under gold catalysis. Conjugation from a remote nitrogen lone pair enables and controls this convergent and highly regioselective process.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 77 شماره
صفحات -
تاریخ انتشار 2013